Top functions affected as a result of altered gene expression. Functions determined by: A. Up-regulated genes after NASP overexpression. B. Down-regulated genes after NASP overexpression. C. Up-regulated genes after NASP depletion. D. Down-regulated genes after NASP depletion. Bars represent -log (p-value) for disproportionate representation of affected genes in the total number of genes in the selected function/disease category. Threshold (red line) denotes the p = 0.05 level.