Figure 1

SAM identification of genes with significant changes in expression. A. Scatter plot of the observed relative difference d(i) versus the expected relative difference dE(i) in cells overexpressing NASP. The solid line indicates the line for d(i) = dE(i), where the observed relative difference is identical to the expected relative difference. The dotted lines are drawn at a distance Delta 11.79 from the solid line. B. Scatter plot of the observed relative difference d(i) versus the expected relative difference dE(i) in cells treated with NASP siRNA. The solid line indicates the line for d(i) = dE(i), where the observed relative difference is identical to the expected relative difference. The dotted lines are drawn at a distance Delta 11.75 from the solid line.