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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells

Figure 4

Serial deletion mapping of region in rat MMP-2 promoter responsible for progesterone inhibition of MMP-2 transcription. (A) Coarse promoter deletion mapping; (B) Fine promoter deletion mapping. (C) Sequence from -1433 to 1342 bp containing progesterone-response region and three potential SP1 binding sites (underlined). White bars: untreated cells (control); black bars: treated cells with progesterone (1 μM).

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