Figure 5
From: Effects and mechanisms of action of sildenafil citrate in human chorionic arteries
Panel A : Cumulative concentration-response curve for sildenafil citrate from 10-7 M to 10-3 M compared to vehicle at a submaximal U46619 induced contraction, in the presence and absence of cGMPS (3 × 10-6 M). Panel B: Cumulative concentration-response curve for sildenafil citrate from 10-7 M to 10-3 M compared to vehicle at a submaximal U46619 induced contraction, in the presence and absence of cGMPS (3 × 10-5 M). *P < 0.05 compared to baseline. †P < 0.05 compared to sildenafil citrate.