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Table 2 Family history of osteoporosis (FHO) and of hip fracture (FHF) regarding ESR1 and ESR2 genotypes.

From: Age-specific effects of estrogen receptors' polymorphisms on the bone traits in healthy fertile women: the BONTURNO study

  FHO FHF FHO-FHF FHO FHF FHO-FHF
  positive negative
ESR1 rs2234693       
CC (n [%]) 39 (17.6) 18 (17.6) 9 (14.7) 77 (24.0) 98 (22.1) 68 (24.1)
CT (n [%]) 118 (53.1) 50 (49.1) 32 (52.5) 158 (49.0) 227 (51.2) 141 (50.0)
TT (n [%]) 65 (29.3) 34 (33.3) 20 (32.8) 87 (27.0) 118 (26.7) 73 (25.9)
Total 222 102 61 322 443 282
ESR2 rs4986938       
AA (n [%]) 36 (16.3) 18 (18.2) 12 (19.7) 50 (15.8) 68 (15.5) 44 (15.8)
AG (n [%]) 104 (47.1) 59 (59.6) 38 (62.3) 119 (37.5) 193 (44.0) 127 (45.5)
GG (n [%]) 81 (36.6) 22 (22.2) 11 (18.0) 148 (46.7) 178 (40.5) 108 (38.7)
Total 221 99 61 317 439 279