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Figure 1 | Reproductive Biology and Endocrinology

Figure 1

From: Identification and characterization of Ca2+-activated K+ channels in granulosa cells of the human ovary

Figure 1

Opening of K Ca channels is required for hCG-stimulated steroidogenesis in human GCs. Blocking of IK (1 μM TRAM-34) and SK channels (100 nM apamin) significantly attenuated hCG (10 IU/ml)-induced progesterone production (PANOVA = 0.0038). According to Newman-Keuls multiple comparison test only the hCG-treated group (*) is significantly different (P < 0.01 compared to all groups), whereas there is no difference between all other groups (P > 0.05). Data represent means ± SEM (n = 3 experiments using independent cell preparations treated on the 3rd day of culture for 24 h).

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