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Table 2 Number of intact and cystic follicles per ovary according to genotype, assigned vaginal signs of estrous cycle stage and follicle diameter.

From: Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice

  Genotype
  MC4R+/+
(n = 7)
MC4R-/-
(n = 13)
MC4R+/+
(n = 9)
MC4R-/-
(n = 4)
Follicle size in μm estrus metestrus
small (100–200) 8.6 (1–17) 13.7 (3–21) 12.6 (3–24) 19.7 (14–28)
large (>200) 7.0 (0–11) 11.7 (4–25) 9.6 (2–20) 13 (6–19)
cystic (>400) 0.5 (0–2) 3.4 (1–7) 0.5 (0–2) 0.25 (0–1)
  1. Ovaries of 3 to 6 months old mice of the first cohort were serially sectioned along the longitudinal plane. Every 4th section was analysed. Follicles were counted as described in Methods. Data are given as means. The numbers in parentheses indicate the range.