From: Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice
 |  | Age (months) | ||||
---|---|---|---|---|---|---|
 |  | 3 | 4 | 5 | 6 | 6 |
Genotype | Estrous cycle | number of animals | ||||
MC4R+/+ | estrus | 1 | 2 | 1 | 3 | 4 |
 | metestrus | 3 | 2 | 2 | 2 | 9 |
MC4R-/- | estrus | 2 | 4 | 3 | 4 | 10 |
 | metestrus | 2 | 0 | 2 | 0 | 3 |
 |  | 1st cohort | 2nd cohort |