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Table 1 Comparisons of cycle characteristics in the agonist and the antagonist groups.

From: Early-cleavage is a reliable predictor for embryo implantation in the GnRH agonist protocols but not in the GnRH antagonist protocols

 

Agonist group

Antagonist group

P value

No. of cycles

331

203

 

ICSI rate

42% (139/331)

43% (87/203)

NS

Age of patients

33.9 ± 0.2 (22–45)

34.4 ± 0.3 (26–46)

NS

Duration of stimulation (days)

11.3 ± 0.1

9.9 ± 0.1

< 0.05

No. of ampoules used per cycle

38.6 ± 0.5

35.4 ± 0.4

NS

Peak E2 level

2347.8 ± 71.9

1731.5 ± 81.1

< 0.0001

No. of oocytes retrieved per cycle

10.0 ± 0.3

8.2 ± 0.4

< 0.05

No. of mature oocytes per cycle

9.0 ± 0.3

7.2 ± 0.3

< 0.05

No. of normal fertilized oocytes per cycle

6.1 ± 0.3 (2019)

5.7 ± 0.3 (1157)

NS

Total no. of embryos

2259

1166

 

Good embryo rate

   

IVF

54.6% (715/1309)a

56.5%(375/664)c

 

ICSI

54.4% (517/950)b

56% (281/502)d

 

No. of embryo transfer

3.8 ± 0.1

3.32 ± 0.9

NS

Embryonic early cleavage rate

   

IVF

34% (450/1309)

20% (133/664)

< 0.0001

ICSI

50% (476/950)

37.8% (190/502)

< 0.0001

Pregnancy rate (%)

   

IVF

46.9% (90/192)

44.8% (52/116)

NS

ICSI

46.8% (65/139)

44.8% (39/87)

NS

Implantation rate

   

IVF

21.9% (160/730)

19% (73/384)

NS

ICSI

21.2% (112/528)

18.9% (55/290)

NS

On going pregnancy rate

   

IVF

35.9% (69/192)

38.8% (45/116)

NS

ICSI

36% (50/139)

39% (34/87)

NS

  1. Note: Values are the mean ± SEM. NS: no significance.
  2. a versus
  3. b: NS.
  4. cversusd: NS.