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Table 1 Comparisons of cycle characteristics in the agonist and the antagonist groups.

From: Early-cleavage is a reliable predictor for embryo implantation in the GnRH agonist protocols but not in the GnRH antagonist protocols

  Agonist group Antagonist group P value
No. of cycles 331 203  
ICSI rate 42% (139/331) 43% (87/203) NS
Age of patients 33.9 ± 0.2 (22–45) 34.4 ± 0.3 (26–46) NS
Duration of stimulation (days) 11.3 ± 0.1 9.9 ± 0.1 < 0.05
No. of ampoules used per cycle 38.6 ± 0.5 35.4 ± 0.4 NS
Peak E2 level 2347.8 ± 71.9 1731.5 ± 81.1 < 0.0001
No. of oocytes retrieved per cycle 10.0 ± 0.3 8.2 ± 0.4 < 0.05
No. of mature oocytes per cycle 9.0 ± 0.3 7.2 ± 0.3 < 0.05
No. of normal fertilized oocytes per cycle 6.1 ± 0.3 (2019) 5.7 ± 0.3 (1157) NS
Total no. of embryos 2259 1166  
Good embryo rate    
IVF 54.6% (715/1309)a 56.5%(375/664)c  
ICSI 54.4% (517/950)b 56% (281/502)d  
No. of embryo transfer 3.8 ± 0.1 3.32 ± 0.9 NS
Embryonic early cleavage rate    
IVF 34% (450/1309) 20% (133/664) < 0.0001
ICSI 50% (476/950) 37.8% (190/502) < 0.0001
Pregnancy rate (%)    
IVF 46.9% (90/192) 44.8% (52/116) NS
ICSI 46.8% (65/139) 44.8% (39/87) NS
Implantation rate    
IVF 21.9% (160/730) 19% (73/384) NS
ICSI 21.2% (112/528) 18.9% (55/290) NS
On going pregnancy rate    
IVF 35.9% (69/192) 38.8% (45/116) NS
ICSI 36% (50/139) 39% (34/87) NS
  1. Note: Values are the mean ± SEM. NS: no significance.
  2. a versus
  3. b: NS.
  4. cversusd: NS.