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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin

Figure 4

(A) Time-course experiment of mean gel area (cm2) ± SEM (indicated by the error bars) 20 mins to 4 hrs 20 mins after thrombin (1 U/ml), hirudin (10 U/ml), thrombin plus hirudin, Y-27632 (2 μM), thrombin plus Y-27632 or control unstimulated cells in collagen. Significance values are indicated for the various treatments compared to the control unstimulated collagen embedded cells, * P < 0.05, ** P < 0.01, *** P < 0.001. (B) Time-course experiment of mean gel area (cm2) ± SEM (indicated by the error bars) 0 to 24 hrs after thrombin (1 U/ml), thrombin plus hirudin (10 U/ml), thrombin plus hirudin plus Y-27632 (10 μM), Y-27632 (10 μM), thrombin plus Y-27632 treatment of hTERT-HM collagen embedded gels versus control unstimulated cells. Significance are indicated for treated cells versus control, ** P < 0.01, *** P < 0.001.

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