Excitatory and inhibitory effects of prolactin release activated by nerve stimulation in rat anterior pituitary

Table 3 PRL concentrations of 10-min sampled perfusate, EFS of 2 min (Mean ± SD, pg/ml)

	Group I	Group J	Group K	Group L
-10	107 ± 1.0	107 ± 1.0	120 ± 1.1	121 ± 0.6
0	152 ± 5.9**	102 ± 4.9	115 ± 5.7	114 ± 5.2
10	105 ± 0.5	105 ± 1.7	119 ± 1.7	118 ± 0.7
20	107 ± 3.9	107 ± 2.2	121 ± 3.2	121 ± 4.0
30	107 ± 1.0	107 ± 1.9	121 ± 1.1	121 ± 2.8
40	104 ± 5.2	103 ± 4.9	115 ± 5.9	115 ± 4.4
50	108 ± 4.0	105 ± 2.2	118 ± 1.3	118 ± 1.5
60	107 ± 3.7	108 ± 2.1	119 ± 3.7	121 ± 2.5
70	107 ± 1.3	108 ± 2.5	120 ± 1.1	121 ± 0.8
80	102 ± 3.9	102 ± 3.7	118 ± 5.0	114 ± 5.0
90	106 ± 0.8	105 ± 1.7	119 ± 2.4	119 ± 1.6
K ⁺	451 ± 23.2**	465 ± 29.0**	633 ± 24.0**	619 ± 34.7**
N	4	4	5	5

Group I: 2 Hz. Group J: 2 Hz + TTX (1 μmol/L). Group K: 10 Hz. Group L: 10 Hz + TTX (1 μmol/L).
The perfusate was continuously collected as aliquots every 10 min and measured by RIA. Italic data represents results during electrical field stimulation.
TTX, tetrodotoxin; EFS, electrical field stimulation; N, the number of the rat used.
*Significant changes within group (** P < 0.01).

ISSN: 1477-7827