Excitatory and inhibitory effects of prolactin release activated by nerve stimulation in rat anterior pituitary

Table 2 PRL concentrations of 1-min sampled perfusate, EFS of 10 min (Mean ± SD, pg/ml)

	Group E	Group F	Group G	Group H
-1	120 ± 2.1	119 ± 2.5	120 ± 1.6	109 ± 0.5
0	137 ± 5.7	114 ± 5.6	132 ± 5.1	104 ± 5.1
1	159 ± 9.3**	117 ± 3.1	144 ± 4.1*	107 ± 0.8
2	182 ± 13.0**	121 ± 2.8	119 ± 7.6**	109 ± 3.3
3	203 ± 7.4**	120 ± 1.4	106 ± 11.0**	111 ± 1.3
4	200 ± 22.5**	115 ± 4.2	94 ± 10.7*	103 ± 3.6
5	200 ± 2.6**	118 ± 1.2	93 ± 5.3*	106 ± 1.6
6	204 ± 11.7**	120 ± 3.0	89 ± 6.0**	109 ± 3.4
7	206 ± 9.9**	120 ± 2.1	84 ± 4.6**	109 ± 0.1
8	196 ± 7.4**	115 ± 5.0	81 ± 6.1**	103 ± 4.9
9	197 ± 5.3**	118 ± 1.7	80 ± 3.3**	108 ± 1.2
K ⁺	568 ± 82.6**	499 ± 36.2**	446 ± 50.4**	489 ± 34.6**
N	5	6	7	4

Group E: 2 Hz. Group F: 2 Hz + TTX (1 μmol/L). Group G: 10 Hz. Group H: 10 Hz + TTX (1 μmol/L).
The perfusate was continuously collected as aliquots every 1 min and measured by RIA. Italic data represents results during electrical field stimulation.
TTX, tetrodotoxin; EFS, electrical field stimulation; N, the number of the rat used.
*Significant changes within group (* P < 0.05, ** P < 0.01).

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