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Table 1 PRL concentrations of 1-min sampled perfusate, EFS of 2 min (Mean ± SD, pg/ml)

From: Excitatory and inhibitory effects of prolactin release activated by nerve stimulation in rat anterior pituitary

  Group A Group B Group C Group D
-1 117 ± 1.0 118 ± 3.3 111 ± 1.3 107 ± 1.0
0 132 ± 13.0 113 ± 7.4 118 ± 5.7 103 ± 5.1
1 153 ± 15.1 * 115 ± 2.6 134 ±3.3 ** 107 ± 1.7
2 184 ± 24.5** 118 ± 4.3 111 ± 6.6 108 ± 3.2
3 214 ± 18.6** 118 ± 1.2 101 ± 6.0 109 ± 1.0
4 214 ± 18.4** 113 ± 4.3 84 ± 3.9** 104 ± 5.8
5 193 ± 32.8** 116 ± 2.6 83 ± 8.6** 107 ± 1.5
6 153 ± 14.9* 115 ± 5.9 93 ± 9.6* 109±2.8
7 131 ± 8.4 117 ± 2.0 105 ± 4.6 108 ± 1.3
8 114 ± 5.3 113 ± 5.0 106 ± 4.6 106 ± 5.3
9 117 ± 3.2 115 ± 3.7 107 ± 1.3 107 ± 1.7
K + 423 ± 42.3** 441 ± 33.4** 382 ± 25.0** 470 ± 35.7**
N 6 5 5 4
  1. Group A: 2 Hz. Group B: 2 Hz + TTX (1 μmol/L). Group C: 10 Hz. Group D: 10 Hz + TTX (1 μmol/L).
  2. The perfusate was continuously collected as aliquots every 1 min and measured by RIA. Italic data represents results during electrical field stimulation.
  3. TTX, tetrodotoxin; EFS, electrical field stimulation; K+, prolactin release was evoked by high potassium (60 mmol/L); N, the number of the rat used.
  4. *Significant changes within group (* P < 0.05, ** P < 0.01).