Table 1 List of unique target genes for ERα and ERβ in HEC1A cell line after E2 treatment

ABCB10

ATP-binding cassette, subfamily B, member 10

AQP3

Aquaporin 3

ADCYAP1

Adenylate cyclase-activating polypeptide 1

B3GAT3

Beta-1,3-glucuronyltransferase 3

AGL

Amylo-1,6-glucosidase, 4-alpha- glucanotransferase

BMP10

Bone morphogenetic protein 10

APRT

Adenine phosphoribosyltransferase

CLU

Clusterin

ARID5B

AT-rich interaction domain-containing protein 5B

COG5

Component of oligomeric golgi complex 5

C3orf1

Chromosome 3 open reading frame 1

CRSP9

Mediator complex subunit 7

CCL11

Chemokine, CC motif, ligand 11

DMBT1

Deleted in malignant brain tumors 1

CCL7

Chemokine, CC motif, ligand 7

DNAH9

Dynein, axonemal, heavy chain 9

CCT6B

Chaperonin-containing T-complex polypeptide 1, subunit 6B

FECH

Protoporphyria, erythropoietic

CD86

Cd86 antigen

FEN1

FLAP structure-specific endonuclease 1

CEACAM3

Carcinoembryonic antigen-related cell adhesion molecule 3

FYB

FYN-binding protein

CLDN4

Claudin 4

GBAS

Glioblastoma amplified sequence

ECM1

Extracellular matrix protein 1

GPX3

Glutathione peroxidase 3

EDN3

Endothelin 3

GRIP1

Glutamate receptor-interacting protein 1

FBLN2

Fibulin 2

HBB

Hemoglobin--beta locus

FOSL1

FOS-like antigen 1

KIAA0427

KIAA0427

GRIK1

Glutamate receptor, ionotropic, kainate 1

LGTN

Ligatin

GSN

Gelsolin

MEF2D

Myocyte enhancer factor 2D

HOXA1

Homeobox A1

NINJ1

Nerve injury-induced protein 1

ITGB7

Integrin, beta-7

PDGFA

Platelet-derived growth factor, alpha polypeptide

ITPA

Inosine triphosphatase

PENK

Proenkephalin

LGALS8

Lectin, galactoside-binding, soluble, 8

PLXNB3

Plexin B3

MB

Myoglobin

PRODH

Proline dehydrogenase

NEK6

Never in mitosis gene a-related kinase 6

SC65

Synaptonemal complex protein SC65

NID2

Nidogen 2

SERPIND1

Heparin cofactor II

ODF2

Outer dense fiber of sperm tails 2

SLC16A4

Solute carrier family 16 (monocarboxylic acid transporter), member 4

POFUT1

Protein o-fucosyltransferase 1

TDG

Thymine-DNA glycosylase

PWP1

PWP1 homolog (S. Cerevisiae)

TFDP1

Transcription factor DP1

RELB

v-rel avian reticuloendotheliosis viral oncogene homolog b

TGM2

Transglutaminase 2

SEC61B

SEC61 complex, beta subunit

TNC

Tenascin C

SFRS16

Splicing factor, arginine/serine- rich 16

TNFRSF10C

Tumor necrosis factor receptor superfamily, member 10c

SGCB

Sarcoglycan, beta

TP63

Tumor protein p63

SPARC

Secreted protein, acidic, cysteine-rich

TRIP10

Thyroid hormone receptor interactor 10

SPATA2

Spermatogenesis-associated protein 2

WFDC2

WAP four-disulfide core domain 2

SSFA2

Sperm-specific antigen 2

TFAP2C

Transcription factor AP2-gamma

TRH

Thyrotropin-releasing hormone deficiency

TRIM16

Tripartite motif-containing protein 16

WNT5A

Wingless-type MMTV integration

site family,

member 5A

XCL2

Chemokine, C motif, ligand 2