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Table 2 Effects of D-aspartate on LH and testosterone release in rat serum

From: The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats

 

Rats treated with placebo

Rats treated with Na-D-Aspartate for 12 days

Rat treated with Na-D-Asp for 12 days and then for 3 days with placebo

LH

(mIU/ml serum)

3.7 ± 0.3

5.6 ± 0.4*

4.1 ± 0.3

Testosterone

(ng/ml serum)

5.1 ± 0.4

10.4 ± 1.2*

6.1 ± 0.5*

  1. A group of 10 male rats (120-130 days old) were allowed to drink a solution of 20 mM NaCl. A second group of rats were allowed to drink a solution of 20 mM of Na-D-aspartate for 12 days and a third group of rats were allowed to drink 20 mM Na-D-aspartate for 12 days and then tap water for 3 days. After treatment each rat was sacrificed and LH and testosterone in serum determined. Values are the mean ± SEM). Asterisks indicate that the difference in the value between treated rats and control rats was significant at p < 0.001, evaluated by one-way ANOVA.