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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Tissue-specific cytokine release from human extra-placental membranes stimulated by lipopolysaccharide in a two-compartment tissue culture system

Figure 3

Summary of LPS-stimulated cytokine release from amnion and choriodecidua in Transwell cultures. Cytokines were released in a distinct manner from the amniotic and choriodecidual sides of human extra-placental gestational membranes exposed to LPS in Transwell cultures. Top: Exposure to LPS on the choriodecidual side of the membranes stimulated choriodecidual release of IL-6, TNF-α, IL-10 and IL-8; TNF-α release increased on the amniotic side, also. Bottom: Exposure to LPS on the amniotic side of the membranes stimulated amniotic release of IL-6 and TNF-α; IL-6, TNF-α, IL-10 and IL-8 increased on the choriodecidual side, also. The wavy lines indicate inflammatory signal transduction across the membranes by an unknown mechanism.

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