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Table 9 Mean gonadotropin doses required to achieve clinical pregnancy/live birth in the 865 ICSI cycles.

From: A comparison of menotropin, highly-purified menotropin and follitropin alfa in cycles of intracytoplasmic sperm injection

  hMG HP-hMG r-hFSH Relative difference, %
     hMG vs r-hFSH HP-hMG vs r-hFSH
Dose per clinical pregnancy, IU* 7563 7258 6536 15.7 11
   ≤35 years 7202 6695 5942 21.2 12.7
   >35 years 8456 8100 8020 5.4 1
Dose per live birth, IU* 10,170 8390 7000 45.3 19.8
   ≤35 years 9690 7739 6364 52.2 21.6
   >35 years 11,371 9364 8589 32.4 9
  1. Mean gonadotropin doses required to achieve one clinical pregnancy or one live birth are presented, with relative differences for hMG and HP-hMG compared with r-hFSH.
  2. *Calculated as the mean dose per cycle/clinical pregnancy rate or live birth rate.
  3. hMG, human menopausal gonadotropin; HP-hMG, highly purified hMG; ICSI, intracytoplasmic sperm injection; r-hFSH, recombinant human follicle-stimulating hormone.