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Table 7 Total gonadotropin dose requirements of the 865 ICSI cycles.

From: A comparison of menotropin, highly-purified menotropin and follitropin alfa in cycles of intracytoplasmic sperm injection

  hMG
(n = 299)
HP-hMG
(n = 330)
r-hFSH
(n = 236)
p value
Total dose, IU 2685 (± 720)a 2903 (± 867)b 2268 (± 747)c < 0.001
(a, b vs c)
Age:     
   ≤35 years 2558 (± 679)a 2678 (± 739)b 2062 (± 681)c <0.001
(a, b vs c)
   >35 years 3002 (± 725)a 3240 (± 935)b 2783 (± 738)c 0.02
(a, b vs c)
Indication:     
   Male factor 2582 ± 641a 2777 ± 859b 2305 ± 606c 0.003
(a, b vs c)
   Mixed factor 2710 ± 751a 2911 ± 892b 2439 ± 770c 0.02
(a, b vs c)
Number of cycles:     
   1 2690 ± 640a 2816 ± 791b 2374 ± 647c 0.003
(a, b vs c)
   2 2670 ± 699a 2942 ± 1,025b 2492 ± 856c 0.003
(a, b vs c)
   ≥3 2601 ± 803a 3071 ± 887b 2486 ± 800c 0.006
(a, b vs c)
  1. Per cycle data are presented by menotropin (hMG), highly-purified menotropin (HP-hMG) or follitropin alfa (r-hFSH). The number of cycles, indication and age-stratified data are shown (mean [± SD]).
  2. hMG, human menopausal gonadotropin; HP-hMG, highly-purified hMG; ICSI, intracytoplasmic sperm injection; r-hFSH, recombinant human follicle-stimulating hormone; SD, standard deviation.