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Table 7 Total gonadotropin dose requirements of the 865 ICSI cycles.

From: A comparison of menotropin, highly-purified menotropin and follitropin alfa in cycles of intracytoplasmic sperm injection

 

hMG

(n = 299)

HP-hMG

(n = 330)

r-hFSH

(n = 236)

p value

Total dose, IU

2685 (± 720)a

2903 (± 867)b

2268 (± 747)c

< 0.001

(a, b vs c)

Age:

    

   ≤35 years

2558 (± 679)a

2678 (± 739)b

2062 (± 681)c

<0.001

(a, b vs c)

   >35 years

3002 (± 725)a

3240 (± 935)b

2783 (± 738)c

0.02

(a, b vs c)

Indication:

    

   Male factor

2582 ± 641a

2777 ± 859b

2305 ± 606c

0.003

(a, b vs c)

   Mixed factor

2710 ± 751a

2911 ± 892b

2439 ± 770c

0.02

(a, b vs c)

Number of cycles:

    

   1

2690 ± 640a

2816 ± 791b

2374 ± 647c

0.003

(a, b vs c)

   2

2670 ± 699a

2942 ± 1,025b

2492 ± 856c

0.003

(a, b vs c)

   ≥3

2601 ± 803a

3071 ± 887b

2486 ± 800c

0.006

(a, b vs c)

  1. Per cycle data are presented by menotropin (hMG), highly-purified menotropin (HP-hMG) or follitropin alfa (r-hFSH). The number of cycles, indication and age-stratified data are shown (mean [± SD]).
  2. hMG, human menopausal gonadotropin; HP-hMG, highly-purified hMG; ICSI, intracytoplasmic sperm injection; r-hFSH, recombinant human follicle-stimulating hormone; SD, standard deviation.