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Table 1 Age-stratified pregnancy and miscarriage rates

From: Miscarriage rates after dehydroepiandrosterone (DHEA) supplementation in women with diminished ovarian reserve: a case control study

 

Age (years)

 

<35

35-37

38-40

41-42

>42

DHEA

     

   Pregnancies

     

   NY

10

5

6

10

9

   TO

7

10

13

0

3

   Miscarriages

     

   NY

1

0

0

2

3

   TO

1

1

3

0

0

   Misc. Rate (%)

     

   NY

10.0

0.0

0.0

20.0

33.3

   TO

14.3

10.0

23.1

-

0.0

   TOTAL

11.8

6.7

15.8

20.0

25.0

   (± 95% CI)

(15.0)

(13.0)

(16.0)

(25.0)

(25.0)

NATIONAL

     

   Misc. Rate (%)

14.0

17.1

23.1

36.6

50.1

   (± 95% CI)

(1.0)

(1.0)

(1.0)

(2.0)

(5.0)

Decrease in Misc. Rate

     

   with DHEA (%)

-15.7

-60.8

-31.6

-45.3

-50.1

  1. Miscarriage rates after DHEA supplementation, stratified for age, were lower at all ages [OR 0.49 (0.25-0.94; p = 0.04)]. The decrease in miscarriage rate was, however, especially apparent above age 35 years.
  2. NY - Center for Human Reproduction, New York;
  3. TO - Toronto West Fertility Associates, Toronto, Canada