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Table 4 Inter-observer variability among and between experienced embryologists and embryology trainees before embryology training sessions indicated by the median (range) value of the kappa coefficient

From: Intra- and inter-observer analysis in the morphological assessment of early-stage embryos

 

Experts vs trainees

Experts vs Experts

Trainees vs Trainees

Parameters day 1

   

Position of the pronuclei

0.27 (0.16-0.52)

0.28 (0-0.49)

0.29 (0.21-0.61)

Size of the pronuclei

0.31 (0.12-0.63)

0.27 (0.23-0.39)

0.14 (0.08-0.43)

Cytoplasmic halo

0.16 (0.03-0.67)

0.44 (0.36-0.52)

0.09 (0.02-0.10)

Parameters day 2

   

Number of blastomeres

0.76 (0.70-0.88)

0.88 (0.82-0.88)

0.67 (0.63-0.79)

Degree of fragmentation

0.43 (0-0.70)

0.60 (0.53-0.61)

0.34 (0.28-0.52)

Size of blastomeres

0.25 (0.02-0.66)

0.52 (0.45-0.53)

0.43 (0.22-0.44)

Pattern of fragmentation

0.36 (0.19-0.42)

0.47 (0.45-0.48)

0.32 (0.20-0.49)

Size of fragments

0.22 (0.01-0.34)

0.52 (0.38-0.83)

0.04 (0-0.14)

Multinucleation

0.16 (0.07-0.32)

0.32 (0.27-0.64)

0.15 (0.07-0.16)

Orientation of the cleavage axes

0.60 (0.32-0.82)

0.79 (0.71-0.79)

0.38 (0.33-0.62)

Parameters day 3

   

Number of blastomeres

0.52 (0.31-0.65)

0.86 (0.73-0.86)

0.44 (0.43-0.51)

Degree of fragmentation

0.18 (0-0.56)

0.35 (0.22-0.56)

0.05 (0.03-0.44)

Size of blastomeres

0.31 (0.06-0.70)

0.40 (0.39-0.50)

0.27 (0.23-0.48)

Pattern of fragmentation

0.28 (0.19-0.49)

0.47 (0.39-0.51)

0.23 (0.22-0.28)

Size of fragments

0.24 (0.07-0.57)

0.43 (0.41-0.45)

0.18 (0.02-0.26)