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Table 4 Inter-observer variability among and between experienced embryologists and embryology trainees before embryology training sessions indicated by the median (range) value of the kappa coefficient

From: Intra- and inter-observer analysis in the morphological assessment of early-stage embryos

  Experts vs trainees Experts vs Experts Trainees vs Trainees
Parameters day 1    
Position of the pronuclei 0.27 (0.16-0.52) 0.28 (0-0.49) 0.29 (0.21-0.61)
Size of the pronuclei 0.31 (0.12-0.63) 0.27 (0.23-0.39) 0.14 (0.08-0.43)
Cytoplasmic halo 0.16 (0.03-0.67) 0.44 (0.36-0.52) 0.09 (0.02-0.10)
Parameters day 2    
Number of blastomeres 0.76 (0.70-0.88) 0.88 (0.82-0.88) 0.67 (0.63-0.79)
Degree of fragmentation 0.43 (0-0.70) 0.60 (0.53-0.61) 0.34 (0.28-0.52)
Size of blastomeres 0.25 (0.02-0.66) 0.52 (0.45-0.53) 0.43 (0.22-0.44)
Pattern of fragmentation 0.36 (0.19-0.42) 0.47 (0.45-0.48) 0.32 (0.20-0.49)
Size of fragments 0.22 (0.01-0.34) 0.52 (0.38-0.83) 0.04 (0-0.14)
Multinucleation 0.16 (0.07-0.32) 0.32 (0.27-0.64) 0.15 (0.07-0.16)
Orientation of the cleavage axes 0.60 (0.32-0.82) 0.79 (0.71-0.79) 0.38 (0.33-0.62)
Parameters day 3    
Number of blastomeres 0.52 (0.31-0.65) 0.86 (0.73-0.86) 0.44 (0.43-0.51)
Degree of fragmentation 0.18 (0-0.56) 0.35 (0.22-0.56) 0.05 (0.03-0.44)
Size of blastomeres 0.31 (0.06-0.70) 0.40 (0.39-0.50) 0.27 (0.23-0.48)
Pattern of fragmentation 0.28 (0.19-0.49) 0.47 (0.39-0.51) 0.23 (0.22-0.28)
Size of fragments 0.24 (0.07-0.57) 0.43 (0.41-0.45) 0.18 (0.02-0.26)