Growth rates of offspring from the pCMV-rAct-injected mice. Body weights of the offspring that were obtained from control and pCMV-rAct-injected mice are shown for the first 6 weeks after birth. The number of offspring used for control and pCMV-rAct-injected mice is 32 (N = 32) and 42 (N = 42), respectively. Asterisks denote values that are significantly different from control mean values (Student's t-test at each point, *, p < 0.01). Values shown are means ± standard deviation.