Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis

Table 3 Endometriosis-specific genes

Tag_Sequence	Neg.	Tags in endom	% in endo	Symbol	Gene name
GAGCCAGGCT	27	1249	96.6	MMP3	Matrix metallopeptidase 3
TGTCATCACA	22	320	76.3	LOXL2	Lysyl oxidase-like 2
TGCAGTCACT	26	317	88.6	MMP1	Matrix metallopeptidase 1
TGCAATAGGT	26	265	90.3	MMP10	Matrix metallopeptidase 10
GCCAGGTGGC	22	244	81.8	MMP2	Matrix metallopeptidase 2
GTATGGGCCC	24	183	88.7	CHI3L1	Chitinase 3-like 1
CCGGGGGAGC	27	158	87.5	COL1A1	Collagen, type I, alpha 1
CAGGAGACCC	28	144	98.1	MMP11	Matrix metallopeptidase 11
CGGGGCGGGG	28	67	83.1	KISS1	KiSS-1 metastasis-suppressor
CCCGCCAGTG	27	59	85.6	ITGA11	Integrin, alpha 11
CTAAGTAGAG	23	59	56.7	undefined	Undefined
GTGCTCAGTG	28	49	78.2	PXDN	Peroxidasin homolog (Drosophila)
GTTTTATGCG	27	48	86.8	DCBLD1	Discoidin, CUB, LCCL domain containing 1
ACAGAGGGGC	28	47	96.2	ABBA-1	Actin-bundling with BAIAP2 homology
CAGTCAATAT	25	43	74.5	FLJ11041	FLJ11041
GTACCGGGGA	27	36	80.5	MMP14	Matrix metallopeptidase 14
GCTAGACGCG	28	29	86.4	FOXL2	Forkhead box L2
CTGTGGTTAC	26	24	77.7	SLC39A13	Solute carrier family 39, member 13
CACACAAACA	27	23	75.0	TWF1	Twinfilin, actin-binding protein, homolog 1
CAGGCCAACC	28	20	91.6	RSU1	Ras suppressor protein 1

"Neg." indicates the number of libraries without detectable expression of the corresponding tags (out of 29 total libraries). "Tag in endom" and "% in endo" indicate the number of tags in endometriosis (per 200,000 total tags), and the percentage of these tags found in endometriosis compared to all the tissues, respectively.

ISSN: 1477-7827