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Table 2 Genes differentially expressed in endometriosis

From: Serial analysis of gene expression reveals differential expression between endometriosis and normal endometrium. Possible roles for AXL and SHC1 in the pathogenesis of endometriosis

Tag_Sequence symbol gene name endom1 endom2 FbEM-1 normen2 Fold
Elevated        
CCAGTGGCCC RPS9 Ribosomal protein S9 64 77 154 0 590
CGAGGGGCCA ACTN4 Actinin, alpha 4 108 50 98 0 512
CTTGGGTTTT IGF2 Insulin-like growth factor 2 (somatomedin A) 28 193 16 0 474
GTATGGGCCC CHI3L1 Chitinase 3-like 1 (cartilage glycoprotein-39) 22 160 10 0 384
GCTGAACGCG CEBPB CCAAT/enhancer binding protein (C/EBP) 29 100 15 0 288
CGCAGTGTCC ATP6V0C ATPase, H+ transporting, lysosomal 16kDa 53 41 31 0 250
TGAAGTTATA ITGB1 Integrin, beta 1 (fibronectin receptor) 39 37 48 0 248
AGCTACCGGG EFEMP2 EGF-containing fibulin-like ECM protein 2 55 11 54 0 240
CGGCTGGTGA PSMB1 Proteasome (prosome, macropain) 32 32 52 0 232
GTGCCCTGTT NCKAP1 NCK-associated protein 1 42 46 20 0 216
TTGCCCCCGT AXL AXL receptor tyrosine kinase 42 51 14 0 214
GCAGTCGCTT DYNLRB1 Dynein, light chain 40 37 28 0 210
CAGCTGGGGC PTBP1 Polypyrimidine tract binding protein 1 27 26 52 0 210
GCCACAGTAC DKFZP586H2123 Regeneration associated muscle protease 42 42 16 0 200
GCCCCGAGCC REEP5 Receptor accessory protein 5 18 34 43 0 190
ACCCCCCCGC JUND Jun D proto-oncogene 35 21 38 0 188
GAAACAAGAT PGK1 Phosphoglycerate kinase 1 19 28 44 0 182
GAGGGGAAAC SHC1 SHC (Src homology 2 domain containing) 40 32 15 0 174
GCCAACAACG NNMT Nicotinamide N-methyltransferase 28 15 42 0 170
TTGCCCAGCA CEECAM1 Cerebral endoth. cell adhesion molecule 1 33 32 17 0 164
Decreased        
GGGCGGAGCT SMARCC2 Myosin, light chain 6 0 0 0 68 136
TAATTTTGAA SNHG5 Small nucleolar RNA host gene 5 0 0 0 50 100
TCCCTATGCT Hs.689482 CDNA FLJ45874 0 0 0 40 80.0
AAGTGTGACG ACTG1 actin, gamma 1 0 0 0 36 72.0
AAATTTTAAA HP1BP3 Heterochromatin protein 1, binding prot 3 0 0 0 31 62.0
TGGTGTTTGG PPIE Peptidylprolyl isomerase E 0 0 0 27 54.0
GGGGATCGGT MRLC2 Myosin regulatory light chain MRLC2 0 0 0 22 44.0
TGGTGTGTGC Hs.684687 cDNA clone ZD94H12 0 0 0 22 44.0
TCCCTATAAA no match Undefined 0 0 0 18 36.0
AGGACAGCAA MYL6 Myosin, light chain 6 0 1 0 40 27.0
TCCCTAGCCC no match Undefined 0 0 1 40 27.0
GCTTATAAAA HINT1 Histidine triad nucleotide binding protein 1 0 0 0 13 26.0
TAAACTGTTT RPS14 Ribosomal protein S14 0 0 0 13 26.0
TATGTGTTTT PAPSS2 3'-phosphoadenos 5'-phosphosulf synth 2 0 0 0 13 26.0
TCCCTTTTAA B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 0 0 0 13 26.0
TTGAAAATTA ANXA2 Annexin A2 0 0 0 13 26.0
TTGGAACAAT no match Undefined 0 0 0 13 26.0
TAGACCCCTT GAPDH Glyceraldehyde-3-phosph dehydrogenase 1 0 0 36 24.0
AAAGGAGAGA NUCB2 Nucleobindin 2 0 0 0 9 18.0
AAGCCTGTAG CAMLG Calcium modulating ligand 0 0 0 9 18.0
  1. The numbers shown represent the number of tags detected in the indicated libraries per 200,000 total tags. "Fold" indicates the ratio of tags detected in endometriosis vs normen2 (for elevated tags) or normen2 vs endometriosis (for decreased tags). A count of zero (0) tag indicates absence of detection (out of 200,000 tags), not necessarily complete absence of expression in the corresponding tissue.