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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate

Figure 4

Proposed model and summary. The statistically significant main effects of Se and isoflavones on gene expression are shown, as well as the significant combined effect of high Se-high isoflavone intake on 5alpha reductase activity. The model shows the role of each gene product in metabolic pathways and the relationship of those pathways to one another. Elucidation of effects on gene expression in this study suggests molecular mechanisms for the individual effects of chemopreventive Se and isoflavones individually, and the potential for an enhanced protective effect by combining the two dietary treatments.

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