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Table 2 Comparison of perinatal outcomes within the thrombophilic and non-thrombophilic groups before and after close surveillance.

From: The impact of close surveillance on pregnancy outcome among women with a prior history of antepartum complications attributed to thrombosis: a cohort study

  Thrombophilic group
(N = 49)
  Non-thrombophilic group
(N = 48)
 
Number of women
with at least one
Before close
surveillance N (%)
After close
surveillance N (%)
P* Before close
surveillance N (%)
After close
surveillance N (%)
P*
Live born neonate 35 (71) 46 (94) 0.004 40 (83) 44(92) 0.1
Preterm delivery 20 (41) 5 (10) 0.001 27 (56) 16 (33) 0.052
Complicated pregnancies 49 (100) 6 (12) <0.001 48 (100) 19 (40) <0.001
SGA 21 (43) 5 (10) <0.001 21 (44) 12 (25) 0.06
IUFD 25 (51) 2 (4) <0.001 20 (42) 3 (6) <0.001
Severe pre-eclampsia 9 (18) 1 (2) 0.02 10 (21) 4 (8) 0.1
Placental abruption 18 (37) 1 (2) <0.001 18 (38) 5 (10) 0.004
  1. * McNemar test
  2. Complicated pregnancies = the reappearance of one or more of the thrombophilic complications considered (fetal death, SGA, severe pre-eclampsia and placental abruption)
  3. SGA = neonate small for gestational age
  4. IUFD = intrauterine fetal death