Figure 6

Numbers of Leydig and Sertoli cells in hpg mice after treatment with estradiol and/or rhFSH. Estimates of numbers of Leydig cells (top) and Sertoli cells (bottom) in testes of hpg mice that had been treated for 50 days with subcutaneous implants containing either cholesterol (chol) or 2% estradiol (E), and also daily treatment with vehicle, 1 or 5 U of recombinant human FSH (Gonal-F™). Values are group mean ± SEM, group sizes as indicated. *P < 0.05 and ***P < 0.001 vs group treated with cholesterol implants and vehicle.