Figure 2From: Effects of estradiol and FSH on maturation of the testis in the hypogonadal (hpg) mouseImmunohistochemical localization of ERα in hpg mice. Examples of immunohistochemical localization of ERα in the pituitary gland (upper panels) or testis of hypogonadal mice (hpg, left panels) or age-matched wild-type mice (+/+, right panels). Note that many anterior pituitary cells express nuclear ERα immunoreactivity in both hpg and +/+ mice. ERα-ir is abundant in the Leydig cells (lc) and peritubular myoid cells (pt) in the testis of hpg mice, and is also present in some Sertoli cells (sc) in wild-type mice. Bottom left panel shows a control study in which the primary antiserum was omitted, the section is from a hpg testis. All photomicrographs were taken at the same magnification so the 20 μm scale bar in top left panel applies to all panelsBack to article page