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Table 2 Serum hormone values in pregnant and lactating rats and in their pups.

From: Treatment of pregnant rats with oleoyl-estrone slows down pup fat deposition after weaning

  

Pregnant/Lactating rats

 
  

P11

P21

L20

ANOVA

Insulin nM

C

0.38 ± 0.06

0.21 ± 0.04

0.18 ± 0.04

 
 

OE

 

0.18 ± 0.04

0.19 ± 0.04

 

Leptin nM

C

0.17 ± 0.01

0.31 ± 0.07

0.09 ± 0.01

T, TR, TxTR

 

OE

 

0.10 ± 0.01*

0.10 ± 0.01

 

Adiponectin nM

C

348 ± 39.8

279 ± 12.3

96.8 ± 25.2

T, TR, TxTR

 

OE

 

144 ± 7.97 *

95.3 ± 17.1

 
   

Pups

 
   

PP20

PP30

ANOVA

Insulin nM

C

 

0.06 ± 0.01

0.10 ± 0.01

T, TxTR

 

OE

 

0.19 ± 0.03*

0.11 ± 0.01

 

Leptin nM

C

 

0.10 ± 0.01

0.18 ± 0.02

TR, TxTR

 

OE

 

0.12 ± 0.01

0.07 ± 0.01*

 

Adiponectin nM

C

 

60.7 ± 6.98

195 ± 12.9

T, TxTR

 

OE

 

69.3 ± 9.03

160 ± 9.93*

 
  1. C: control group; OE: treated group. Values are expressed as the mean ± s.e.m. of 6 animals per group. Statistical analysis of the differences: Two-way ANOVA (time (T), treatment (TR) and interaction (TxTR)) was performed.
  2. Post-hoc Bonferroni test (comparison between C and OE): * = P < 0.01
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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