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Table 1 Serum metabolite values in pregnant and lactating rats and their fetuses/pups.

From: Treatment of pregnant rats with oleoyl-estrone slows down pup fat deposition after weaning

   Pregnant/Lactating rats  
      P11    P21    L20 ANOVA
Glucose mM C 6.81 ± 0.20 6.98 ± 0.52 7.77 ± 0.11  
  OE   5.58 ± 0.48 * 6.87 ± 0.07  
Protein g/l C 64.4 ± 1.42 64.5 ± 2.13 53.2 ± 1.01 T, TxTR
  OE   63.4 ± 1.43 60.8 ± 2.16 *  
Urea mM C 6.05 ± 0.32 5.29 ± 0.33 10.3 ± 0.41 T
  OE   5.61 ± 0.71 11.1 ± 0.98  
Non-esterified C 0.21 ± 0.01 0.95 ± 0.04 0.62 ± 0.10 T, TxTR
fatty acids mM OE   1.07 ± 0.04 0.41 ± 0.05 *  
3OH butyrate μM C 93.2 ± 8.22 106 ± 15.3 90.1 ± 18.9 T
  OE   99.8 ± 9.42 38.7 ± 3.53 *  
Cholesterol mM C 0.88 ± 0.06 0.83 ± 0.07 3.74 ± 0.23 T, TxTR
  OE   0.49 ± 0.06 4.11 ± 0.18  
HDL Cholesterol mM C 0.44 ± 0.03 0.48 ± 0.08 0.34 ± 0.05  
  OE   0.30 ± 0.01 * 0.39 ± 0.06  
Triacylglycerols mM C 1.25 ± 0.09 1.90 ± 0.04 0.52 ± 0.04 T
  OE   1.93 ± 0.08 0.57 ± 0.06  
   Fetus/Pups  
      F21    PP20    PP30 ANOVA
Glucose mM C 4.01 ± 0.21 7.83 ± 0.11 8.84 ± 0.12 T, TR, TxTR
  OE 3.16 ± 0.12 * 7.84 ± 0.09 8.12 ± 0.12 *  
Protein g/l C 24.7 ± 1.40 40.8 ± 0.94 44.2 ± 1.74 T, TR, TxTR
  OE 21.1 ± 0.40 49.6 ± 1.40 * 55.1 ± 1.21 *  
Urea mM C 5.37 ± 0.83 5.79 ± 0.90 5.24 ± 0.38  
  OE 5.87 ± 0.70 4.36 ± 0.42 4.95 ± 0.58  
Non-esterified C 0.24 ± 0.01 0.49 ± 0.06 0.59 ± 0.04 T
fatty acids mM OE 0.21 ± 0.02 0.57 ± 0.11 0.64 ± 0.01  
3OH butyrate μM C 288 ± 3.64 250 ± 7.31 91.5 ± 14.1 T, TxTR
  OE 297 ± 3.25 211 ± 15.9 * 108 ± 7.47  
Cholesterol mM C 1.15 ± 0.06 3.46 ± 0.11 2.13 ± 0.09 T
  OE 0.98 ± 0.13 3.27 ± 0.18 2.07 ± 0.01  
HDL cholesterol mM C 0.12 ± 0.02 0.15 ± 0.01 0.18 ± 0.02 T, TxTR
  OE 0.08 ± 0.03 0.15 ± 0.02 0.35 ± 0.08 *  
Triacylglycerols mM C 0.27 ± 0.04 2.03 ± 0.01 1.67 ± 0.16 T
   0.41 ± 0.11 1.91 ± 0.07 1.52 ± 0.13  
  1. C: control group; OE: treated group. Values are expressed as the mean ± s.e.m. of 6 animals per group. Statistical analysis of the differences: Two-way ANOVA (time (T), treatment (TR) and interaction (TxTR)) was performed.
  2. Post-hoc Bonferroni test (comparison between C and OE): * = P < 0.01