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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Morphological evidences indicate that the interference of cimetidine on the peritubular components is responsible for detachment and apoptosis of Sertoli cells

Figure 4

Electron micrograph of portion of seminiferous tubule of rat from CmG. The epithelial basal lamina (Bl) and the inner basal lamina (Bli) of myoid cell (M) are infolded. Between these laminae, a thick layer of type I collagen fibrils is observed (asterisks). In the SC plasma membrane, the hemidesmosome-like junctions are detached from the Bl (white arrowheads) and surrounded by a thin layer of amorphous matrix (inset; arrowhead). The SC nucleus is dislocated from the basal region and exhibits two portions: (A) an electron dense portion containing fragmented chromatin irregularly distributed and (B) an electron lucent portion with a thin granular chromatin homogeneously distributed. The portion "A" contains a block of condensed chromatin (white asterisk). Mitochondria with tubular cristae (Mi); lipid inclusions (Li). ×8,960; Inset: ×19,700.

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