Figure 2

E-cadherin immunoreactivity in the epithelial cells of cystic mouse ovaries. A. OSE to mesothelial junction of an ovary from a 6-month BR mouse; negative control without primary antibody. B. A small amount of E-cadherin immunoreactivity can be seen in the OSE, but not the mesothelium of a serial section to A. C. Strong junctional E-cadherin immuno-staining in extra-ovarian rete ovarii from a 6-month IO mouse. D. E-cadherin immuno-staining in an intra-ovarian rete ovarii tubule from a 6-month IO mouse. E. Ciliated cells lining a hilar ovarian inclusion cyst show E-cadherin immunoreactivity, whereas flatter cells lining the cyst are unstained. F. Cells lining a cortical inclusion cyst from a 9-month IO ovary showing very little membrane-bound E-cadherin immuno-staining. Insert shows the negative control without primary antibody. G. Lack of E-cadherin junctional immuno-staining in some, but not all cells lining an inclusion cyst connected to the ovarian hilus, in a 6-month IO ovary. H. Strong membrane-limited E-cadherin immunoreactivity in cells of papillae in a cortical inclusion cyst from a 12-month IO ovary.