Figure 2

Box and whisker plots are shown depicting the semi-quantitative immunohistochemical staining (HSCORE ± SD) for ER-alpha in normal women throughout the menstrual cycle in proliferative, early, mid and late secretory glandular (A) and luminal (B) epithelium and in stroma (C). In a separate analysis, glandular and luminal ER-alpha HSCOREs were compared between normal fertile mid-secretory endometrium and similar samples in women with endometriosis and suspected defects in uterine receptivity (D). Significance was based on ANOVA with Bonferroni correction; * = p < 0.01, ** = p < 0.001. Abbreviations in the figure: Prolif = proliferative phase, ES = early secretory, MS = mid-secretory, LS = last secretory, gl = glandular epithelium, St = stroma, LU = luminal epithelium, Osis = endometrium from women with endometriosis. Note that the horizontal bars in the box and whisker plots designate the 10^th, 25^th, 50^th, 75^th, and 90^th percentile distribution of the data and standard error bars are not shown in this figure.