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Figure 1 | Reproductive Biology and Endocrinology

Figure 1

From: Differential expression of members of the E2F family of transcription factors in rodent testes

Figure 1

Stage-specificity of spermatogonial renewal, proliferation, differentiation, and its regulation, as reviewed by Dirk G. de Rooij [1]. Abbreviations: As = spermatogonial stem cell, Apr = paired spermatogonia, Aal-n = aligned spermatogonia of n number of cells, An = differentiated type A spermatogonia entering synchronised division number n, In = intermediate type spermatogonia, B = B-type spermatogonia which undergo final mitotic division before replication and division for Meiosis I, GDNF/Ret are the ligand/receptor tyrosine kinase complex for glial cell-line derived neurotrophic factor (GDNF) signaling, GFRα1 is the glycosyl-phosphatidylinositol (GPI)-achored coreceptor for GDNF/Ret, SCF/c-kit are the ligand/receptor complex for stem cell factor (SCF) signaling, Dazl is the deleted in azoospermia-like gene, and Bax and Bcl-XL are pro-apoptopic and anti-apoptopic Bcl-2 protein family members respectively.

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