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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells

Figure 3

Methylation profiles of two retrotransposables elements, intracisternal-A particle (IAP) and murine endogenous retrovirus-L (MuERV-L) in R1p16 and R1p27 ES cells. (A) Regions analyzed by bisulphite sequencing in IAP and MuERV-L. LTR, long terminal repeat. Filled circles represent CpG dinucleotides present in the regions analysed. (B) Individual DNA methylation profile following bisulphite treatment and amplification of ES cell DNA. Methylated and unmethylated regions are represented by filled circles and open circles, respectively. The overall percentage of methylated CpG dinucleotides is shown above each group of clones.

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