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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Follicle-stimulating hormone (FSH) activates extracellular signal-regulated kinase phosphorylation independently of beta-arrestin- and dynamin-mediated FSH receptor internalization

Figure 4

Inhibition of dynamin- or β-arrestin-mediated FSH-R internalization does not impair FSH-induced ERK phosphorylation. A: Immunodetection of P-ERK, of endogenous β-arrestins and of β-arrestin (319–418) as indicated, following 4, 8 and 12 min of FSH stimulation. n.s. = non specific. MWM = molecular weight marker (kDa). B: Quantification of P-ERK in response to 8 min of FSH stimulation (n = 3 independent experiments).

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