Table 2 TCDD-inducible genes in human AEC

Enzyme

Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6

2.46

1.92

33.82

NM_021615

Cytochrome P450 1A1

6.79

10.36

20.74

NM_000499

Cytochrome P450 1B1

3.99

7.13

19.36

NM_000104

Dehydrogenase/reductase (SDR family) member 2

2.57

3.17

26.62

NM_182908

Fucosyltransferase 2 (secretor status included)

2.85

1.99

27.64

NM_000511

Matrix metalloproteinase 9

4.49

4.67

23.58

NM_004994

Membrane metallo-endopeptidase

2.75

2.88

27.60

NM_007287

Podocalyxin-like

3.50

3.83

22.26

NM_005397

Poly (ADP-ribose) polymerase family, member 12

4.02

4.57

26.69

NM_022750

Stearoyl-CoA desaturase

2.56

2.06

27.95

AB032261

Uridine phosphorylase 1

2.56

2.40

31.76

NM_003364

Transcription Factor

Distal-less homeo box 2

3.05

2.50

24.50

NM_004405

Interferon regulatory factor 7

2.82

4.46

25.21

NM_004030

Interferon-stimulated transcription factor 3, gamma 48 kDa

1.54

3.78

25.44

NM_006084

N-myc (and STAT) interactor (NMI)

2.61

3.30

26.18

NM_004688

Nuclear antigen Sp100

1.06

2.28

29.04

NM_003113

Tumor necrosis factor, alpha-induced protein 3

2.50

2.18

25.94

NM_006290

v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)

3.33

3.75

27.11

NM_012323

Signal Transducer

GABA-B receptor

2.59

2.56

29.53

AF056085

Signal transducer and activator of transcription 1

2.84

2.85

21.55

NM_007315

Structural Protein and Other Groups

Amphiregulin

2.80

10.70

22.56

NM_001657

Epiregulin

4.18

3.19

27.35

NM_001432

Epithelial membrane protein 1

3.01

2.84

25.54

NM_001423

FLJ20035

11.16

5.58

30.53

NM_017631

Insulin induced gene 1

2.53

2.61

26.85

NM_005542

Integrin, alpha 10

2.72

1.91

25.04

AF112345

Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

2.42

3.54

25.17

NM_002203

Interferon induced transmembrane protein 1

5.31

31.85

27.24

NM_003641

Interferon, alpha-inducible protein

12.65

18.72

21.80

NM_005101

Interferon, alpha-inducible protein 27

12.13

16.84

23.13

NM_005532

Interferon-induced protein with tetratricopeptide repeats 1

177.99

158.71

26.34

NM_001001887

Keratin 6A

3.23

4.45

21.99

NM_005554

Ras-related associated with diabetes

2.72

2.42

23.57

NM_004165

Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2

11.00

12.36

24.86

NM_002575

Small proline-rich protein 3

2.97

3.56

22.33

NM_005416

Tripartite motif-containing 14

4.61

2.56

27.43

NM_014788

Tumor necrosis factor

3.89

3.04

26.79

NM_000594

Function Unknown

Pleckstrin homology-like domain, family A, member 1

2.81

5.13

27.91

NM_007350