Figure 3From: Sexually dimorphic gene expression that overlaps maturation of type II pneumonocytes in fetal mouse lungsHypothesis concerning the expression profile ofsome differentially expressed genes Our previous results suggest that Cyp21a1 is expressed at different precise gestation time on GD 15 for each gender [27] as shown in the present figure. This hypothesis would explain why the expression profile of Cyp21a1 on GD15.5 varied from litter to litter and presented one of the following patterns : 1) high expression in female fetal lungs only; 2) high expression in male fetal lungs only; or 3) no elevated expression in male and female fetal lungs. Because Balb/C is an inbred strain, the mating window of 16h would explain the variation between litters. Genes presenting such an expression profile cannot be studied by microarrays from a pool of many litters because the sex difference in expression could be lost.Back to article page