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Table II IGFBPs and estradiol in follicular fluid from future dominant and subordinate follicles prior to deviation.

From: Evidence of a local negative role for cocaine and amphetamine regulated transcript (CART), inhibins and low molecular weight insulin like growth factor binding proteins in regulation of granulosa cell estradiol production during follicular waves in cattle

Parameters Future dominant follicle Future subordinate follicle #1 Future subordinate follicle #2
Diameter (mm) 7.6 ± 0.4 6.9 ± 0.4 6.1 ± 0.4*
Follicular fluid estradiol (E; ng/ml) 113 ± 30 44 ± 11* 40 ± 13*
Follicular fluid progesterone (P; ng/ml) 21 ± 3 42 ± 27 14 ± 3
E:P ratio 5.2 ± 0.8 3.1 ± 0.8* 2.7 ± 0.4*
IGFBP-2 (Arbitrary units) 12 ± 2 18 ± 4 14 ± 5
IGFBP-3 (Arbitrary units) 203 ± 17 245 ± 28 197 ± 36
IGFBP-4 (Arbitrary units) 1 ± 0.3 14 ± 7* 11 ± 4*
IGFBP-5 (Arbitrary units) 13 ± 2 32 ± 10 24 ± 8
  1. * Significantly different (P < 0.05) from the future dominant follicle (Adapted from Mihm et al., 2000 [10])