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Figure 2 | Reproductive Biology and Endocrinology

Figure 2

From: Evidence of a local negative role for cocaine and amphetamine regulated transcript (CART), inhibins and low molecular weight insulin like growth factor binding proteins in regulation of granulosa cell estradiol production during follicular waves in cattle

Figure 2

Dose response effect of α2-macroglobulin on bovine granulosa cell estradiol production. Granulosa cells from dominant nonovulatory follicles were treated for 18 hours with different amounts of bovine IgG (control), bovine α2-macroglobulin (bα2-m) or human α2-macroglobulin (hα2-m). Bars represent the overall mean ± SEM values for concentrations of estradiol in media after culture of granulosa cells isolated from two follicles (n = 2 cows). Different letters above bars indicate significant (P < 0.01) difference among means. Reproduced from Ireland et al., 2004 [101].

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