Figure 1

ZAR1 protein and mRNA sequences comparison between pig, cattle and human. (A) Alignment of porcine and bovine ZAR1 with human protein. Numbers indicate amino acid position. Identical amino acids are boxed in grey. Zinc finger, FYVE/PHD-type domain is underlined by circle points. Exon boundaries are defined by bent arrows. Start methionin amino acids (M) are in bold; note putative alternative start M sites in porcine (amino acid 183) and human (amino acid 173). (B) Porcine (Ss), bovine (Bt) and human (Hs) ZAR1 3'-- end cDNA alignment. 3-UTRs are in lower-case letters. Coding sequence is in capital letters. Termination codons are bold-typed. Identical nucleotides are denoted by stars. Protein sequence is in bold-type italic. Hexamer polyadenylation signals are double-underlined. Putative Pumilio-binding sites are outlined. U/purines dinucleotide-rich stretches (putative EDEN) are boxed in grey.