Table 1 Gene ontology categories significantly (p < 0.05) overrepresented among the 381 gene transcripts up-regulated in the testis of ABP-transgenic mice*
P-value | Number of transcripts | Percent | GO category |
|---|---|---|---|
0.00708 | 46 | 12.07 | Membrane |
0.00759 | 22 | 5.77 | Genes located on chromosome 3 |
0.0449 | 11 | 2.89 | GPCR signaling pathway |
0.03895 | 11 | 2.89 | Catalytic activity |
0.0129 | 9 | 2.36 | Immune response |
0.03625 | 7 | 1.84 | Peptidase activity |
0.03774 | 7 | 1.84 | Rhodopsin-like receptor activity |
0.00798 | 7 | 1.84 | Cytoskeleton organization and biogenesis |
0.00225 | 6 | 1.57 | Chemotaxis |
0.01054 | 5 | 1.31 | Intermediate filament |
0.04126 | 5 | 1.31 | Serine-type endopeptidase activity |
0.00641 | 5 | 1.31 | Muscle development |
0.0152 | 5 | 1.31 | Lyase activity |
1.5E-4 | 4 | 1.05 | Steroid binding |
0.00786 | 4 | 1.05 | Sodium ion transport |
0.02409 | 4 | 1.05 | Serine-type endopeptidase inhibitor activity |
0.00862 | 3 | 0.79 | Peroxidase activity |
<1.0E-5 | 3 | 0.79 | GP signaling, coupled to IP3 second messenger (phospholipase C activating) |
0.04783 | 3 | 0.79 | Steroid hormone receptor activity |
0.03299 | 3 | 0.79 | Heterotrimeric G-protein complex |
0.04461 | 3 | 0.79 | Ligand-dependent nuclear receptor activity |
0.02793 | 3 | 0.79 | Lipid catabolism |
0.03571 | 3 | 0.79 | Symporter activity |
0.00561 | 3 | 0.79 | Response to oxidative stress |
0.03855 | 3 | 0.79 | Regulation of transcription |
4.9E-4 | 3 | 0.79 | Structural constituent of eye lens |