Table 2 Theoretical and actual FSH bioactivities for Bravelle®, Menopur®, and a mixture of Bravelle® and Menopur® when reconstituted in 0.9% saline and mixed in the same syringe.
Hormone (FSH:LH)a | Theoretical bioactivity IU/mL (%) | Actual bioactivity IU/mL (% claim) | L-valueb |
|---|---|---|---|
Bravelle® (75:0) | 75 (100%) | 76.58 (102.1%) | 0.072 |
Menopur® (75:75) | 75 (100%) | 76.0 (101.3%) | 0.072 |
Bravelle® + Menopur® | |||
(150:75) | 150 (100%) | 156.86 (104.6%) | 0.072 |
(300:75) | 300 (100%) | 308.69 (102.9%) | 0.072 |
(300:225) | 300 (100%) | 306.58 (102.2%) | 0.072 |