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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Peptidylarginine deiminase (PAD) is a mouse cortical granule protein that plays a role in preimplantation embryonic development

Figure 3

Multiple alignments of mammalian PAD protein sequences. The sequences were aligned using the program MultiAlin available at http://prodes.toulouse.inra.fr/multalin/multalin.html. The peptide sequence (VLIGGSFY) of p75 obtained from MS/MS analysis was searched against listed PADs and residues that were matched to it are marked (*). The signal peptide cleavage site is marked with an arrow. The monopartite nuclear localization sequence in human PAD V is underlined. High consensus sequences are in red (90% of amino acids are identical or have biochemically similar R-groups) and low consensus sequences are in blue (50% of amino acids are identical or have biochemically similar R-groups). The abbreviations of species are listed as followed: Mm = M. musculus; Rn = R. norvegicus; Hs = H. sapiens. Two putative mouse PAD sequences are referred with their accession numbers (GenBank/NCBI). Accession numbers (GenBank/NCBI) of other PADs are as followed: NP_694746; XP_233601; NP_035189; NP_035190; NP_036519; NP_032838.

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