Table 3 Clinical profile of diabetic patients and controls with and without PCO
Clinical Parameter | Diabetic subjects | Controls | P value (ANOVA) | ||
|---|---|---|---|---|---|
PCO (n = 64) | Non-PCO (n = 41) | PCO (n = 22) | Non-PCO (n = 38) | ||
Age (years), Mean ± SD | 36.8 ± 4.28* | 35.2 ± 4.4 | 34.2 ± 4.5 | 35.5 ± 4.6 | 0.000 |
Duration of DM (y), Mean ± SD | 4.19 ± 2.0 | 2.9 ± 1.6 a | -- | -- | 0.000 |
Age of menarche (y), Mean ± SD | 13.5 ± 0.8 | 13.50 ± 0.6 | 13.1 ± 0.8 | 13.1 ± 0.7 | 0.015 |
Menstrual irregularity, | 24 (37.5%) | 4 (9.8%) | 0 | 0 | 0.000 |
Oligomenorrhea | 12 (18.8%) | 1 (2.4%) | |||
Polymenorrhea | 1 (1.6%) | 1 (2.4%) | |||
Mennorrhagia | 11 (17.2%) | 2 (4.9%) | |||
Infertility | 4 (6.2%) | 0 | 0 | 0 | 0.368 |
Hirsuitism | 9 (14.1%) | 0 | 4 (18.2%) | 2 (5.3%) | 0.030 |
Acne | 3 (4.7%) | 0 | 1 (4.5%) | 1 (2.6%) | 0.564 |
Acanthosis | 2 (3.1%) | 0 | 0 | 0 | 0.368 |
History of hypertension | 40 (78%) | 30 (73%) | 0 | 0 | 0.000 |
SBP (mmHg), Mean ± SD | 140 ± 12.7 | 139 ± 12.3 | 138 ± 9.5 | 130 ± 9.3 b | 0.000 |
DBP (mmHg), Mean ± SD | 85.8 ± 7.8 | 83.3 ± 7.3 | 82.1 ± 10.2 | 80.58 ± 7.5 | 0.012 |
BMI (kg/m2), Mean ± SD | 25.8 ± 3.1 | 24.7 ± 3.3 | 26.36 ± 2.8 | 25.34 ± 3.3 | 0.180 |
Waist to hip ratio, Mean ± SD | 0.94 ± 0.6 | 0.92 ± 0.7 | 0.94 ± 0.6 | 0.92 ± 0.6 | 0.426 |
Ovarian volume (ml), Mean ± SD | 5.80 ± 1.18 | 4.13 ± 1.07 | 5.98 ± 1.28 | 3.89 ± 0.88 | 0.000 |
PCOS† | 39 (61%) | 0 | 15 (68%) | 0 | 0.000 |