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Table 2 Effects of mouse recombinant IFN-γ on erythrophagocytosis exhibited by trophoblast cells from IFN-γRα-/- mice

From: Interferon-gamma alters the phagocytic activity of the mouse trophoblast

Culture treatment

n

PI (%)

Rα -/- mice

SCM (standard culture medium)

4

14.72 ± 4.05

 

SCM + mrIFN-γ (100 U/mL)

5

14.99 ± 10.88

Congenic animals

SCM (standard culture medium)

4

11.52 ± 4.65

 

SCM + mrIFN-γ (100 U/mL)

3

33.46 ± 5.72 *, **

  1. * Values significantly different compared to cultures using IFN-γ-treated and untreated Rα-/- mice (p <0.05), **compared to cultures of congenic animals that did not receive IFN-γ (p < 0.01) (ectoplacental cone from wild type mice). PI, phagocytic index calculated as the percentage of trophoblast giant cells containing erythrophagosomes. SCM, standard culture medium.