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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Interferon-gamma alters the phagocytic activity of the mouse trophoblast

Figure 3

Effect of (A) mrIFN-γ and (B) monoclonal antibody XMG 1.2 anti-IFN-γ on the erythrophagocytosis exhibited by NZW Ă— AKR F1 gd-7.5 trophoblast cells. (A) Ectoplacental cones were cultured for 48 h in the mrIFN-γ concentrations indicated in the graphics. Note that the highest phagocytic activity occurs at the concentration of 100 U/mL. The cultures that received the monoclonal antibody (B, 0–200 μg/mL), also received 200 μL/mL of leukocyte-conditioned medium (LCM). Data represent the mean ± SD of three separate experiments and asterisks show statistical differences in relation to the control (p < 0.05).

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