Figure 2
From: Interferon-gamma alters the phagocytic activity of the mouse trophoblast
Cultured trophoblast cells from NZW Ă— AKR F1 (A-C) and IFN-γRα-/- mice (D). (A) Cells of ectoplacental cone cultured in the presence of erythrocytes in standard culture medium show no phagosomes (final magnification, Ă— 8,500), (B-D) whereas the cytoplasm of trophoblast cells stimulated with mrIFN-γ exhibit large numbers of erythrophagosomes (*). In the electron micrograph (C), different stages of erythrocyte internalization are seen (↑). (â–², free erythrocytes) (B, toluidine blue, Ă— 640; C, Ă— 5,500; D, Ă— 16,500).