Skip to main content

Table 1 Antiuterotrophic activity of 17α-E2 in adult ovariectomized rats.

From: Evidence that 17alpha-estradiol is biologically active in the uterine tissue: Antiuterotonic and antiuterotrophic action

Dosage of 17α-E2 (μmol/day/Kg body weight)

Ratioaof 17β-E2:17α-E2

Uterine wet weight/100 gb

% inhibitionc

0.3

1:1

266.1 ± 8.2

18.55

0.9

1:3

229.9 ± 10.7

29.63

1.5

1:5

228.3 ± 10.4

30.11

30.0

1:100

213.1 ± 7.8

34.77

  1. aFixed dose of 17β-E2 used = 0.3 μmol/day/Kg body weight.
  2. bData from six independent experiments ± SEM (six rats per group).
  3. cAs compared with uterotrophic effect of 17β-E2.