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Table 1 Antiuterotrophic activity of 17α-E2 in adult ovariectomized rats.

From: Evidence that 17alpha-estradiol is biologically active in the uterine tissue: Antiuterotonic and antiuterotrophic action

Dosage of 17α-E2 (μmol/day/Kg body weight) Ratioaof 17β-E2:17α-E2 Uterine wet weight/100 gb % inhibitionc
0.3 1:1 266.1 ± 8.2 18.55
0.9 1:3 229.9 ± 10.7 29.63
1.5 1:5 228.3 ± 10.4 30.11
30.0 1:100 213.1 ± 7.8 34.77
  1. aFixed dose of 17β-E2 used = 0.3 μmol/day/Kg body weight.
  2. bData from six independent experiments ± SEM (six rats per group).
  3. cAs compared with uterotrophic effect of 17β-E2.