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Table 1 Percentage of embryos after intrafollicular administration of IL-1β or IL-1RA in equine dominant follicles.

From: In vivo effect of interleukin-1beta and interleukin-1RA on oocyte cytoplasmic maturation, ovulation, and early embryonic development in the mare

 

Number of injected follicles

Percent of embryos

PBS i.f., saline i.v. (negative control group)

12

67 (8/12)a

IL-1RA i.f., saline i.v. (IL-1RA group)

12

25 (3/12)b

IL-1β i.f., saline i.v. (IL-1β group)

13

23 (3/13)b

PBS i.f., CEG i.v. (positive control group)

12

67 (8/12)a

IL-1RA i.f., CEG i.v. (IL-1RA/CEG group)

13

23 (3/13)b

  1. PBS, Phosphate buffer saline; CEG, crude equine gonadotropin; IL-1β, interleukin 1 beta; IL-1RA, interleukin 1 receptor antagonist; i.f., intrafollicular; i.v., intravenous. a and b are significantly different (p < 0.05).