Effect of anti-α6 IgG on cell numbers, proliferation and pyknotic rates of GC from small follicles cultured on substrata containing different ratios of LN and RGD peptides. GC from small follicles were cultured for 144 h as described in legend of Figure 5. (a): numbers of cells at 144 h of culture; (b): proliferation rates of GC at 48 h of culture; (c): pyknotic rates of GC at 48 h of culture. Empty bars: control; solid bars: with anti-α6 IgG in culture medium. Data represent mean ± SEM of 6 independent experiments. * : p < 0.05, ** : p < 0.01, *** : p < 0.001, with vs. without anti-α6 IgG.